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Nutrtion Guide Home > NCI Cancer Thesaurus > WAS Gene

WAS Gene
Definition and Synonyms

Definition: WAS gene encodes for Wiskott-Aldrich syndrome (WAS) family of proteins, which share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. The phenotype Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene.(from Gene)

Synonyms: WAS Gene, IMD2, THC, WAS, WASP, Wiskott-Aldrich syndrome Gene

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