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Zinc Finger Protein-265
Definition and Synonyms

Definition: A product of a developmentally regulated gene expressed in differentiated renal myoepithelioid juxtaglomerular cells located in the afferent arteriole at the entrance to the glomerulus. Their main function and distinctive feature is the synthesis and release of renin, the key hormone-enzyme of the renin-angiotensin system that regulates arterial blood pressure. Zis protein reveals transcription factor activity and was shown to contain zinc fingers and domains characteristic of splicing factors and RNA binding proteins.

Synonyms: Zinc Finger Protein-265, Zis-Protein-265

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