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Early Response Protein-NAK1
Definition and Synonyms

Definition: Nuclear Receptor Subfamily 4, Group A, Member 1, encoded by the NR4A1 gene, is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Its expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. This protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Three transcript variants encoding two distinct isoforms have been identified for this gene. (from LocusLink)

Synonyms: Nuclear Receptor Subfamily 4, Group A, Member 1, Early Response Protein NAK1, Growth Factor Response Protein 1, Growth Factor-Inducible Nuclear Protein N10, Hormone Receptor, NR4A1, Nuclear Hormone Receptor TR3, Orphan Nuclear Receptor HMR, Steroid Receptor TR3, TR3 Orphan Receptor

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