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Janus Kinase-2
Definition and Synonyms

Definition: This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constitutively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. (from LocusLink)

Synonyms: Janus Kinase 2, EC 2.7.1.112, JAK-2, JAK2, Tyrosine-Protein Kinase JAK2

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