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Nutrtion Guide Home > NCI Cancer Thesaurus > C-C Motif Chemokine Receptor-9

C-C Motif Chemokine Receptor-9
Definition and Synonyms

Definition: Expressed in placenta, lung, lymphatic endothelia, lymph nodes, intestinal mucosa/submucosa, hemopoietic cells, and fetal liver by human CCBP2 Gene (GPCR1/Beta Chemokine Receptor Family), Chemokine (C-C Motif) Receptor 9 is a seven transmembrane G protein-coupled receptor for many beta chemokines (MCP1, MIP1-alpha, RANTES, MCP3) and is critical for recruitment of effector immune cells to inflammation sites. CCBP2 does not mediate intracellular calcium flux but may function in chemokine-driven recirculation of leukocytes. (NCI)

Synonyms: Chemokine (C-C Motif) Receptor 9, C-C Chemokine Receptor D6, C-C Chemokine Receptor Type 9, CC-Chemokine Receptor CCR10, CC-Chemokine-Binding Receptor JAB61, CCBP2, CCR-9, CCR10, CCR9, CMBRK9, Chemokine Binding Protein 2, Chemokine-Binding Protein D6, D6, hD6

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