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C-C Motif Chemokine Receptor-6
Definition and Synonyms

Definition: Chemokine (C-C Motif) Receptor 6, encoded by the CCR6 gene, is a member of the beta chemokine receptor family and a seven transmembrane protein similar to G protein-coupled receptor. The CCR6 gene is preferentially expressed by immature dendritic cells and memory T cells. This receptor mediates intracellular calcium flux and binds specifically to the CC chemokine macrophage inflammatory protein 3 alpha (MIP-3 alpha). It is important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. (From LocusLink and NCI)

Synonyms: Chemokine (C-C Motif) Receptor 6, BN-1, C-C CKR-6, C-C Chemokine Receptor Type 6, CC-CKR-6, CCR-6, CCR6, CCR6 Protein, CKR-L3, CKR6, CKRL3, CMKBR6, Chemokine (C-C) Receptor 6, Chemokine Receptor-Like 3, DCR2, DRY-6, DRY6, G Protein-Coupled Receptor 29, GPR-CY4, GPR29, GPRCY4, LARC Receptor, STRL22, Seven-Transmembrane Receptor, Lymphocyte, 22

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