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IFITM1 Gene
Definition and Synonyms

Definition: Controlled by IFN-alpha and -gamma, the two-exon human IFITM1 Gene (IFN-Induced Transmembrane Protein Family) on chromosome 11 encodes 125-amino acid 14-kD Interferon-Induced Transmembrane Protein 1 (Fragilis), a membrane protein component of a multimeric complex involved in transduction of antiproliferative and homotypic adhesion signals. Fragilis appears to demarcate germ cells from somatic neighbors and mark the onset of germ cell competence. (from LocusLink, Swiss-Prot, OMIM, and NCI)

Synonyms: IFITM1 Gene, IFI17, IFITM1, LEU13

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