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L-Leucyl-L-Leucine Methyl Ester
Definition and Synonyms

Definition: A lysosomotropic agent taken up by cells and converted to pro-apoptotic metabolites that are membranolytic for cytotoxic T-cells, Natural Killer (NK) cells, and Lymphokine-activated Killer (LAK) cells. Studies have treated donor cells ex-vivo with L-Leucyl-L-Leucine Methyl Ester (LLME) to test its ability to prevent Graft Versus Host Disease(GVHD).

Synonyms: L-Leucyl-L-Leucine Methyl Ester

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