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C-Terminal Binding Protein-1
Definition and Synonyms

Definition: The phosphoprotein C-Terminal Binding Protein 1 (CTBP-1), encoded by the CTBP1 gene, is a transcriptional repressor targeting diverse transcription regulators. CTBP1 binds the C-terminus of adenovirus E1A protein. It also interacts with ELK3 and CTIP via their consensus motif. CTBP1 may play a role during cellular proliferation, adenovirus replication and oncogenic transformation. The level of phosphorylation may be regulated during the cell cycle.CTBP1 can form homodimers or heterodimers of CTBP1 and CTBP2. (From LocusLink, Swiss_Prot)

Synonyms: C-Terminal Binding Protein 1, CTBP1

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