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FABP2 Gene
Definition and Synonyms

Definition: The FABP2 gene encodes Fatty Acid-Binding Protein 2, which belongs to the fatty-acid binding protein (FABP) family thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. The FABP2 gene has a polymorphism in position 54, which changes Ala-54 (71% of the population) to Thr-54 (29%). The Thr-54 allele has a 2-fold greater affinity for long-chain fatty acids than the Ala-54 allele. Thr-54 is associated with increased fat oxidation and insulin resistance. (from LocusLink and Swiss-Prot)

Synonyms: FABP2 Gene, FABP2, FABPI, I-FABP

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