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H19 Gene
Definition and Synonyms

Definition: In humans the H19 gene is expressed exclusively from the maternal chromosome. Its product is reported to be an untranslated RNA. The gene is a developmentally regulated gene with putative tumor suppressor activity. H19 expression in developing skeletal and smooth muscles correlates with specific differentiation events in these tissues. Its accumulation increases during skeletal muscle development with maximal accumulation in adulthood and no expression in other tissues. Expression of H19 in skeletal muscle correlates with nonproliferative, actin-positive muscle cells. Loss of H19 expression may be involved in Wilms tumorigenesis. (from OMIM and NCI) )

Synonyms: H19 Gene, ASM, ASM1, D11S813E, H19, MGC4485

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