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N-Myristoyltransferase-2
Definition and Synonyms

Definition: Dioxins are potent mammalian carcinogens and toxins affecting liver, skin, and immune and reproductive systems. N-myristoyltransferase 2 (NMT2) is one of the later dioxin-inducible genes. NMT2 and induced protein myristoyltransferase activity are direct responses to carcinogen exposure. Because inappropriate protein NH(2)-terminal myristoylation appears to play a role in carcinogenesis, induction of NMT2 may play a central role in dioxin carcinogenicity. (from Cancer Res 2001;61:8534-9)

Synonyms: N-Myristoyltransferase 2, EC 2.3.1.97, Glycylpeptide N-Tetradecanoyltransferase 2, NMT2

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