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Nutrtion Guide Home > NCI Cancer Thesaurus > ABL2 Gene

ABL2 Gene
Definition and Synonyms

Definition: Human ABL2 Gene (ABL family) at 1q24-q25 produces a 12 kb transcript that encodes a widely expressed cytoplasmic tyrosine kinase with SH2 and SH3 domains. Isoforms IA and IB are produced by alternative splicing. ABL2 is fused with ETV6 in AML translocation t(1;12)(q25;p13) and is also involved in CML. (from SWISS-PROT, OMIM, and NCI)

Synonyms: ABL2 Gene, ABL2, ABLL, ARG, Abelson Murine Leukemia Viral Oncogene Homolog 2, Abelson Related Gene

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