Nutrtion Guide Home > NCI Cancer Thesaurus > ID2 Protein

ID2 Protein
Definition and Synonyms

Definition: A member of the "ID" subfamily, ID2 promotes cell cycle progression by inhibiting RB, p107, and p130. By increasing ID2 expression, MYC overrides RB suppression of ID2 action. Since ID2 lacks a DNA-binding domain it must work through dimerization with other HLH transcription factors. (from SWISS-PROT Q02363, OMIM 600386, and NCI)

Synonyms: ID2 Protein, DNA-Binding Protein Inhibitor ID-2, ID2, Inhibitor of DNA Binding 2, Inhibitor of DNA Binding 2, Dominant Negative Helix-Loop-Helix Protein, Inhibitor of Differentiation 2

To search for ID2 Protein on the web, just click the search button below.

Click on a letter to find infomation NCI Cancer and related disease terms starting with that letter.

A | B | C | D | E | F | G | H | I | J | K | L | M
N | O | P | Q | R | S | T | U | V | W | X | Y | Z