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Nutrtion Guide Home > NCI Cancer Thesaurus > ABC Transporter

ABC Transporter
Definition and Synonyms

Definition: ABC transporters consist of two integral membrane proteins (permeases) each having six transmembrane segments, two peripheral membrane proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. The ATP-binding protein component is the most conserved, the membrane protein component is somewhat less conserved, and the substrate-binding protein component is most divergent.

Synonyms: ABC Transporter, ABC Transport Protein, ABC Transporter Protein, ATP Binding Cassette Transporter

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