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G-Quartets
Definition and Synonyms

Definition: G-quadruplexes are multi-stranded structures held together by square planes of four guanines ('G-quartets') interacting by forming Hoogsteen hydrogen bonds. G-quartet structures has been developed as novel anti-HIV agents. Several critical structure-activity relationships between HIV-1 integrase and G-quartet oligonucleotides have been demonstrated.

Synonyms: G-Quartets, G-Quadruplex, G-Quadruplexes, G-Quadruplexes DNA, G-Quartet Structures, G-Tetrads, G4-DNA

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