Treating chronic mutational hepatitis B with Chinese medicine Vitalliver (Vigconic suppositories) by ZHANG GUAN HUA, LIANG CHAO, ZHENG WAN PIN

Treating chronic mutational hepatitis B with Chinese medicine Vitalliver (Vigconic suppositories)

ZHANG GUAN HUA, LIANG CHAO, ZHENG WAN PIN

Chengdu University of TCM, Hepatitis Laboratory in the attached hospital of Chengdu University of TCM, Sichuan, China

Research Method:

Quantitative determination by contrasting HBV-DNA of cases before and after the treatment.

Number of cases: 25 (n)

Case Selection: Between the age of 16 and 65, in accordance with the diagnosis standards pf chronic Hepatitis B, with negative e antigen and positive e antibody, HBV-DNA > 1×104 cp/mL.

Detection Method: All the blood samples are detected by Sichuan Clinical Detection Center; PCR-ELISA quantitative determination is used within detection range of 1×104 - 1×107-8, HBV-DNA, unit of measurement is cp/mL.

Direction Plan: one suppository provided by Vigconic (International) Ltd. Bid. The course of treatment is six months, the tracing observation after withdrawal lasts six months.

Observation index:

1.HBV-DNA response after the treatment.

2.Lasting HBV-DNA response (six months after withdrawal).

Criterion of Therapeutic Effect:

1.If HBV-DNA volume < 1×104 cp/mL, it is considered effective;

2.Compared with that before the treatment, if the HBV-DNA volume decreases at least two logarithmic levels, it is considered progressive;

3.If there is no change in HBV-DNA volume after the treatment, or the decrease is less than two logarithmic levels, it is considered ineffective.

Judging Levels of the side-effects: (five levels) definitely related, probably related, possibly related, possibly unrelated, definitely unrelated.

Result

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BIO:

Chengdu University of TCM, Hepatitis Laboratory in the attached hospital of Chengdu University of TCM, Sichuan, China

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