How to Avoid Dangerous Drug-Herb Interactions, Part 2
by Brian B. Carter, MS, LAc
11. Valerian
Valerian should not be combined with barbituates.
12. Kelp
Kelp as a source of iodine may interfere with thyroid replacement therapies.
13. Echinacea
Echinacea could cause liver toxicity and therefore should not be used with other known liver toxic drugs, such as anabolic steroids, amiodarone, methotrexate, and ketoconazole
14. Nonsteroidal anti-inflammatory drugs may negate the usefulness of feverfew in the treatment of migraine headaches
15. Kava when used with alprazolam has resulted in coma
16. Evening primrose oil and borage should not be used with anticonvulsants because they may lower the seizure threshold.
17. Both Rhubard and Aloe cause loss of potassium through the stool... this may increase the side effects of cardiac glycosides and antiarrhythmic drugs.
18. Astragalus (huang qi) may oppose immunosupressive drugs, because it tends to improve immune function.
Some of these herbs are not chinese herbs (feverfew, gingko, valerian, kava, echinacea, everning primrose, borage). If you saw a Chinese herbalist, they wouldn't be an issue. Plus, chinese herbalists prescribe more balanced formulas, not single herbs, so potential interactions with the single herbs are reduced.
Positive Drug Herb Interactions
Gan cao increases the effectiveness of prednisone. This benefit can be used to reduce the dosage of prednisone in patients who have to take it long term. This reduces the serious long-term side effects (bone density loss, adrenal insufficiency, etc.).
In typhoid fever, research showed that those given an herbal formula (xue yang mei) plus a sulfa drug did better than those just given the sulfa drug. Both groups had a 100% cure rate, but the combination group experienced few or no side effects.
In mastitis, those given a heat and toxin clearing herbal formula (jin yin hua, pu gong ying, yu jin, chi shao, dan shen, qing pi) plus penicillin/streptomycin injections did much better than those only given the injection.
In adult primary nephrotic syndrome, one group was simply given corticosteroids, while another group was also given an herb formulas (dan shen, di gu pi, gui ban, han lian cao, hong hua, nu zhen zi, gou qi zi, sheng di, zhi mu). The steroid only group had a recovery rate of 56%, while the combined group's recovery rate was 85%. In another study with nephritic patients, patients given predisone, zhi mu (anemarrhena), shu di huang (rehmannia), and gan cao (licorice) experienced less of the corticosteroid side effects.
Late-stage gastric cancer patients were studied. All patients were given a drug chemotherapy combo of either methotrexate, fluoroacil and vinblastine, or methotrexate, MFC, and fluorocil. One of the two groups was also given herbs (huang qi, tai zhi shen, caulis banthalobi, ji xue tang, bai zhu, fu ling, niu zhen zi, gou qi zi, tu su zi). Side effects were cut in half or eliminated in the chemo plus herbs group.
Solving the Multi-Drug Problem with Herbs
Many patients are on multiple drugs. We have had success reducing these medications over time with the assistance of herbal formulas. An appropriate herbal formula is begun weeks or months ahead of time. This gives the patient a 'cushion,' so to speak. Then the drug dosage is slowly reduced. The herbal prescription is modified as the patient progresses. MD's often cooperate with us in this effort since they know as well as anyone the dangers of poly-pharmacy (taking multiple drugs at once)… especially in the elderly. They say a good geriatric doctor stops more medications than he starts.
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BIO:
Acupuncturist, herbalist, and medical professor Brian B. Carter founded the alternative health megasite The Pulse of Oriental Medicine (http://www.PulseMed.org/). He is the author of the book "Powerful Body, Peaceful Mind: How to Heal Yourself with Foods, Herbs, and Acupressure" (November, 2004). Brian speaks on radio across the country, and has been quoted and interviewed by Real Simple, Glamour, and ESPN magazines.
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